Cayman Chemical DMHAPC-Chol 25mg
A non-competitive allosteric inhibitor of IL-8/CXCL8 activation of CXCR1 and CXCR2 chemokine receptors (IC50s 1 and 100 nM respectively) blocks IL-8-induced leukocyte recruitment (IC50 1 nM) and other inflammatory responses without affecting receptor activation induced by other CXCR1 and CXCR2 agonists at 100 nM depletes a cancer stem cell population in human breast cancer cell lines in vitro